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T95 nucleophosmin phosphorylation as a novel mediator and marker of regulated cell death in acute kidney injury
The function of site-specific phosphorylation of nucleophosmin (NPM), an essential Bax chaperone, in stress-induced cell death is unknown. We hypothesized that NPM threonine 95 (T95) phosphorylation both signals and promotes cell death. In resting cells, NPM exclusively resides in the nucleus and T9...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Physiol Renal Physiol |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7509286/ https://ncbi.nlm.nih.gov/pubmed/32686519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00230.2020 |
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