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Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer’s disease pathology

Neuronal activity can modify Alzheimer’s disease pathology. Overexcitation of neurons can facilitate disease progression whereas the induction of cortical gamma oscillations can reduce amyloid load and improve cognitive functions in mouse models. Although previous studies have induced cortical gamma...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wilson, Caroline A., Fouda, Sarah, Sakata, Shuzo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508947/
https://ncbi.nlm.nih.gov/pubmed/32963298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72421-9
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