Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

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Опубликовано в: :Front Aging Neurosci
Главные авторы: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://ncbi.nlm.nih.gov/pubmed/34322015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.703876
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