Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

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Udgivet i:Front Aging Neurosci
Main Authors: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://ncbi.nlm.nih.gov/pubmed/34322015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.703876
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