Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

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Bibliografski detalji
Izdano u:Front Aging Neurosci
Glavni autori: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://ncbi.nlm.nih.gov/pubmed/34322015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.703876
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