Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

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Bibliografische gegevens
Gepubliceerd in:Front Aging Neurosci
Hoofdauteurs: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://ncbi.nlm.nih.gov/pubmed/34322015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.703876
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