Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://ncbi.nlm.nih.gov/pubmed/34322015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.703876
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