Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV

While antiretroviral therapy (ART) can completely suppress viremia, it is not a cure for HIV. HIV persists as a latent reservoir of infected cells, able to evade host immunity and re-seed infection following cessation of ART. Two promising immunotherapeutic strategies to eliminate both productively...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Powell, Allison B., Ren, Yanqin, Korom, Maria, Saunders, Devin, Hanley, Patrick J., Goldstein, Harris, Nixon, Douglas F., Bollard, Catherine M., Lynch, Rebecca M., Jones, R. Brad, Cruz, Conrad Russell Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508916/
https://ncbi.nlm.nih.gov/pubmed/33005704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.015
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