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Suboptimal Dosing of Fluconazole in Critically Ill Patients: Time To Rethink Dosing

Fluconazole is frequently used for the treatment of invasive Candida infections in critically ill patients. However, alterations in renal functions might influence fluconazole clearance. Therefore, our objective was to study the impact of renal function on the population pharmacokinetics of fluconaz...

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發表在:Antimicrob Agents Chemother
Main Authors: Muilwijk, Eline W., de Lange, Dylan W., Schouten, Jeroen A., Wasmann, Roeland E., ter Heine, Rob, Burger, David M., Colbers, Angela, Haas, Pieter J., Verweij, Paul E., Pickkers, Peter, Brüggemann, Roger J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508595/
https://ncbi.nlm.nih.gov/pubmed/32816723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00984-20
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