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Suboptimal Dosing of Fluconazole in Critically Ill Patients: Time To Rethink Dosing

Fluconazole is frequently used for the treatment of invasive Candida infections in critically ill patients. However, alterations in renal functions might influence fluconazole clearance. Therefore, our objective was to study the impact of renal function on the population pharmacokinetics of fluconaz...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Muilwijk, Eline W., de Lange, Dylan W., Schouten, Jeroen A., Wasmann, Roeland E., ter Heine, Rob, Burger, David M., Colbers, Angela, Haas, Pieter J., Verweij, Paul E., Pickkers, Peter, Brüggemann, Roger J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508595/
https://ncbi.nlm.nih.gov/pubmed/32816723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00984-20
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