Population Pharmacokinetic Model and Pharmacokinetic Target Attainment of Micafungin in Intensive Care Unit Patients

OBJECTIVE: To study the pharmacokinetics of micafungin in intensive care patients and assess pharmacokinetic (PK) target attainment for various dosing strategies. METHODS: Micafungin PK data from 20 intensive care unit patients were available. A population-PK model was developed. Various dosing regi...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Martial, Lisa C., ter Heine, Rob, Schouten, Jeroen A., Hunfeld, Nicole G., van Leeuwen, Henk J., Verweij, Paul E., de Lange, Dylan W., Pickkers, Peter, Brüggemann, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591795/
https://ncbi.nlm.nih.gov/pubmed/28144840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0509-5
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