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Sources of variation in cell-type RNA-Seq profiles

Cell-type specific gene expression profiles are needed for many computational methods operating on bulk RNA-Seq samples, such as deconvolution of cell-type fractions and digital cytometry. However, the gene expression profile of a cell type can vary substantially due to both technical factors and bi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gustafsson, Johan, Held, Felix, Robinson, Jonathan L., Björnson, Elias, Jörnsten, Rebecka, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505444/
https://ncbi.nlm.nih.gov/pubmed/32956417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239495
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