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EGFR forms ligand-independent oligomers that are distinct from the active state
The human epidermal growth factor receptor (EGFR/ERBB1) is a receptor tyrosine kinase (RTK) that forms activated oligomers in response to ligand. Much evidence indicates that EGFR/ERBB1 also forms oligomers in the absence of ligand, but the structure and physiological role of these ligand-independen...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7504936/ https://ncbi.nlm.nih.gov/pubmed/32727847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012852 |
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