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Physical Basis behind Achondroplasia, the Most Common Form of Human Dwarfism
Fibroblast growth factor receptor 3 (FGFR3) is a receptor tyrosine kinase that plays an important role in long bone development. The G380R mutation in FGFR3 transmembrane domain is known as the genetic cause for achondroplasia, the most common form of human dwarfism. Despite many studies, there is n...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943285/ https://ncbi.nlm.nih.gov/pubmed/20624921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094086 |
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