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Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry

Peptidyl fluoromethyl ketones occupy a pivotal role in the current scenario of synthetic chemistry, thanks to their numerous applications as inhibitors of hydrolytic enzymes. The insertion of one or more fluorine atoms adjacent to a C-terminal ketone moiety greatly modifies the physicochemical prope...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Citarella, Andrea, Micale, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504820/
https://ncbi.nlm.nih.gov/pubmed/32899354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25174031
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