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Reagents for Selective Fluoromethylation: A Challenge in Organofluorine Chemistry

The introduction of a monofluoromethyl moiety has undoubtedly become a very important area of research in recent years. Owing to the beneficial properties of organofluorine compounds, such as their metabolic stability, the incorporation of the CH(2)F group as a bioisosteric substitute for various fu...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Reichel, Marco, Karaghiosoff, Konstantin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383490/
https://ncbi.nlm.nih.gov/pubmed/32022357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201913175
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