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An improved method for the incorporation of fluoromethyl ketones into solid phase peptide synthesis techniques
An improved and expedient technique for the synthesis of peptidyl-fluoromethyl ketones is described. The methodology is based on prior coupling of an aspartate fluoromethyl ketone to a linker and mounting it onto resin-bound methylbenzhydrylamine hydrochloride. Subsequently, by utilising standard Fm...
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| Publicado no: | RSC Adv |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185805/ https://ncbi.nlm.nih.gov/pubmed/34178310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1ra03046a |
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