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Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors—A Possible Involvement of DC-STAMP

It is well established that multinucleation is central for osteoclastic bone resorption. However, our knowledge on the mechanisms regulating how many nuclei an osteoclast will have is limited. The objective of this study was to investigate donor-related variations in the fusion potential of in vitro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Møller, Anaïs M. J., Delaissé, Jean-Marie, Olesen, Jacob B., Canto, Luisa M., Rogatto, Silvia R., Madsen, Jonna S., Søe, Kent
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504560/
https://ncbi.nlm.nih.gov/pubmed/32887359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176368
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