Aging and menopause reprogram osteoclast precursors for aggressive bone resorption

Women gradually lose bone from the age of ~35 years, but around menopause, the rate of bone loss escalates due to increasing bone resorption and decreasing bone formation levels, rendering these individuals more prone to developing osteoporosis. The increased osteoclast activity has been linked to a...

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Bibliografiske detaljer
Udgivet i:Bone Res
Main Authors: Møller, Anaïs Marie Julie, Delaissé, Jean-Marie, Olesen, Jacob Bastholm, Madsen, Jonna Skov, Canto, Luisa Matos, Bechmann, Troels, Rogatto, Silvia Regina, Søe, Kent
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329827/
https://ncbi.nlm.nih.gov/pubmed/32637185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-020-0102-7
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