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Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors—A Possible Involvement of DC-STAMP

It is well established that multinucleation is central for osteoclastic bone resorption. However, our knowledge on the mechanisms regulating how many nuclei an osteoclast will have is limited. The objective of this study was to investigate donor-related variations in the fusion potential of in vitro...

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Publicat a:Int J Mol Sci
Autors principals: Møller, Anaïs M. J., Delaissé, Jean-Marie, Olesen, Jacob B., Canto, Luisa M., Rogatto, Silvia R., Madsen, Jonna S., Søe, Kent
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504560/
https://ncbi.nlm.nih.gov/pubmed/32887359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176368
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