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Knockdown of α2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion

Aberrant sialylation is frequently found in pancreatic ductal adenocarcinoma (PDA). α2,3-Sialyltransferases (α2,3-STs) ST3GAL3 and ST3GAL4 are overexpressed in PDA tissues and are responsible for increased biosynthesis of sialyl-Lewis (sLe) antigens, which play an important role in metastasis. This...

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Bibliografske podrobnosti
izdano v:	Int J Mol Sci
Main Authors:	Guerrero, Pedro Enrique, Miró, Laura, Wong, Bin S., Massaguer, Anna, Martínez-Bosch, Neus, de Llorens, Rafael, Navarro, Pilar, Konstantopoulos, Konstantinos, Llop, Esther, Peracaula, Rosa
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI 2020
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7503936/ https://ncbi.nlm.nih.gov/pubmed/32872308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176239
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Knockdown of α2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion

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