Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease

Asymptomatic and symptomatic Alzheimer’s disease (AD) subjects may present with equivalent neuropathological burdens but have significantly different antemortem cognitive decline rates. Using the transcriptome as a proxy for functional state, we selected 414 expression profiles of symptomatic AD sub...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Canchi, Saranya, Raao, Balaji, Masliah, Deborah, Rosenthal, Sara Brin, Sasik, Roman, Fisch, Kathleen M., De Jager, Philip L., Bennett, David A., Rissman, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503200/
https://ncbi.nlm.nih.gov/pubmed/31340147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.073
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