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Mapping the gene network landscape of Alzheimer's disease through integrating genomics and transcriptomics.
Integration of multi-omics data with molecular interaction networks enables elucidation of the pathophysiology of Alzheimer's disease (AD). Using the latest genome-wide association studies (GWAS) including proxy cases and the STRING interactome, we identified an AD network of 142 risk genes and...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2022-02-01
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| Edice: | PLoS Computational Biology |
| On-line přístup: | https://doi.org/10.1371/journal.pcbi.1009903 |
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