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Multiplexed conditional genome editing with Cas12a in Drosophila

CRISPR-Cas genome engineering has revolutionized biomedical research by enabling targeted genome modification with unprecedented ease. In the popular model organism Drosophila melanogaster, gene editing has so far relied exclusively on the prototypical CRISPR nuclease Cas9. Additional CRISPR systems...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Port, Fillip, Starostecka, Maja, Boutros, Michael
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502738/
https://ncbi.nlm.nih.gov/pubmed/32843348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004655117
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