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A general strategy for engineering noncanonical amino acid dependent bacterial growth
Synthetic auxotrophy in which bacterial viability depends on the presence of a synthetic amino acid provides a robust strategy for the containment of genetically modified organisms and the development of safe, live vaccines. However, a simple, general strategy to evolve essential proteins to be depe...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7501724/ https://ncbi.nlm.nih.gov/pubmed/31580059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08491 |
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