Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and elevated suicide risk. To determine genetic differences between common clinical sub-phenotypes of BD, we performed a systematic polygenic risk score (PRS) analysis using multiple PRSs from a range of psych...

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Publicat a:Transl Psychiatry
Autors principals: Coombes, Brandon J., Markota, Matej, Mann, J. John, Colby, Colin, Stahl, Eli, Talati, Ardesheer, Pathak, Jyotishman, Weissman, Myrna M., McElroy, Susan L., Frye, Mark A., Biernacka, Joanna M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501305/
https://ncbi.nlm.nih.gov/pubmed/32948743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00996-y
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