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Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder

Bipolar disorder (BD) is highly heterogeneous in symptomatology. Narrowing the clinical phenotype may increase the power to identify risk genes that contribute to particular BD subtypes. This study was designed to test the hypothesis that genetic overlap between schizophrenia (SZ) and BD is higher f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Markota, Matej, Coombes, Brandon J., Larrabee, Beth R., McElroy, Susan L., Bond, David J., Veldic, Marin, Colby, Colin L., Chauhan, Mohit, Cuellar-Barboza, Alfredo B., Fuentes, Manuel, Kung, Simon, Prieto, Miguel L., Rummans, Teresa A., Bobo, William V., Frye, Mark A., Biernacka, Joanna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131184/
https://ncbi.nlm.nih.gov/pubmed/30201969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0242-3
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