Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and elevated suicide risk. To determine genetic differences between common clinical sub-phenotypes of BD, we performed a systematic polygenic risk score (PRS) analysis using multiple PRSs from a range of psych...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Coombes, Brandon J., Markota, Matej, Mann, J. John, Colby, Colin, Stahl, Eli, Talati, Ardesheer, Pathak, Jyotishman, Weissman, Myrna M., McElroy, Susan L., Frye, Mark A., Biernacka, Joanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501305/
https://ncbi.nlm.nih.gov/pubmed/32948743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00996-y
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