Model-informed Bayesian Estimation Improves the Prediction of Morphine Exposure in Neonates and Infants

BACKGROUND: Pain control in infants is an important clinical concern, with potential long-term adverse neurodevelopmental effects. Intravenous morphine is routinely administered for post-operative pain management; however, its dose-concentration-response relationship in neonates and infants has not...

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Detaylı Bibliyografya
Yayımlandı:Ther Drug Monit
Asıl Yazarlar: Euteneuer, Joshua C., Mizuno, Tomoyuki, Fukuda, Tsuyoshi, Zhao, Junfang, Setchell, Kenneth D. R., Muglia, Louis J., Vinks, Alexander A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501088/
https://ncbi.nlm.nih.gov/pubmed/32427759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000763
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