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Utility of microminipigs for evaluating liver-mediated gene expression in the presence of neutralizing antibody against vector capsid
Adeno-associated virus (AAV) vectors can transduce hepatocytes efficiently in vivo in various animal species, including humans. Few reports, however, have examined the utility of pigs in gene therapy. Pigs are potentially useful in preclinical studies because of their anatomical and physiological si...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Gene Ther |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7500982/ https://ncbi.nlm.nih.gov/pubmed/32066928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-020-0125-0 |
| Ετικέτες: |
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