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Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit
We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1 expresses normal LTP and spatial memory, assayed by the Morris water maze. Our results support a model in which LTP generates synaptic slots...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7500950/ https://ncbi.nlm.nih.gov/pubmed/32831170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58042 |
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