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Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 (TIMP3) Axis in Diabetic Nephropathy

BACKGROUND: Long non-coding RNAs (lncRNAs) play vital roles in development of diabetic nephropathy (DN). The goal of our study was to investigate the functional roles of long intergenic noncoding RNA (lincRNA) 4930556M19Rik in DN. MATERIAL/METHODS: A DN cell model was constructed by exposing podocyt...

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Bibliographic Details
Published in:Med Sci Monit
Main Authors: Fan, Hong, Zhang, Weiwei
Format: Artigo
Language:Inglês
Published: International Scientific Literature, Inc. 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500124/
https://ncbi.nlm.nih.gov/pubmed/32896839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.925361
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