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Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 (TIMP3) Axis in Diabetic Nephropathy

BACKGROUND: Long non-coding RNAs (lncRNAs) play vital roles in development of diabetic nephropathy (DN). The goal of our study was to investigate the functional roles of long intergenic noncoding RNA (lincRNA) 4930556M19Rik in DN. MATERIAL/METHODS: A DN cell model was constructed by exposing podocyt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Fan, Hong, Zhang, Weiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500124/
https://ncbi.nlm.nih.gov/pubmed/32896839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.925361
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