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A novel target enrichment strategy in next-generation sequencing through 7-deaza-dGTP-resistant enzymatic digestion
OBJECTIVE: Owing to the overwhelming dominance of human and commensal microbe sequences, low efficiency is a major concern in clinical viral sequencing using next-generation sequencing. DNA composed of 7-deaza-2′-deoxyguanosine 5′-triphosphate (c(7)dGTP), an analog of deoxyguanosine triphosphate (dG...
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| Udgivet i: | BMC Res Notes |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7499927/ https://ncbi.nlm.nih.gov/pubmed/32948245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05292-y |
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