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Bifrost: highly parallel construction and indexing of colored and compacted de Bruijn graphs

Memory consumption of de Bruijn graphs is often prohibitive. Most de Bruijn graph-based assemblers reduce the complexity by compacting paths into single vertices, but this is challenging as it requires the uncompacted de Bruijn graph to be available in memory. We present a parallel and memory-effici...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Holley, Guillaume, Melsted, Páll
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499882/
https://ncbi.nlm.nih.gov/pubmed/32943081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02135-8
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