Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine

BACKGROUND & AIMS: Vitamin D exerts regulatory roles via vitamin D receptor (VDR) in mucosal immunity, host defense, and inflammation involving host factors and microbiome. Human Vdr gene variation shapes the microbiome and VDR deletion leads to dysbiosis. Low VDR expression and diminished vitam...

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Detaylı Bibliyografya
Yayımlandı:Cell Mol Gastroenterol Hepatol
Asıl Yazarlar: Zhang, Yong-Guo, Lu, Rong, Wu, Shaoping, Chatterjee, Ishita, Zhou, David, Xia, Yinglin, Sun, Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498955/
https://ncbi.nlm.nih.gov/pubmed/32497792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.05.010
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