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Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine

BACKGROUND & AIMS: Vitamin D exerts regulatory roles via vitamin D receptor (VDR) in mucosal immunity, host defense, and inflammation involving host factors and microbiome. Human Vdr gene variation shapes the microbiome and VDR deletion leads to dysbiosis. Low VDR expression and diminished vitam...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Zhang, Yong-Guo, Lu, Rong, Wu, Shaoping, Chatterjee, Ishita, Zhou, David, Xia, Yinglin, Sun, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498955/
https://ncbi.nlm.nih.gov/pubmed/32497792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.05.010
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