Intestinal epithelial HMGB1 inhibits bacterial infection via STAT3 regulation of autophagy

Extracellular HMGB1 (high mobility group box 1) is considered as a damage-associated molecular pattern protein. However, little is known about its intracellular role. We studied the mechanism whereby intestinal epithelial HMGB1 contributes to host defense, using cell culture, colonoids, conditional...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Zhang, Yong-Guo, Zhu, Xiaorong, Lu, Rong, Messer, Jeannette S., Xia, Yinglin, Chang, Eugene B., Sun, Jun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844505/
https://ncbi.nlm.nih.gov/pubmed/30894054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596485
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