Intestinal epithelial HMGB1 inhibits bacterial infection via STAT3 regulation of autophagy

Extracellular HMGB1 (high mobility group box 1) is considered as a damage-associated molecular pattern protein. However, little is known about its intracellular role. We studied the mechanism whereby intestinal epithelial HMGB1 contributes to host defense, using cell culture, colonoids, conditional...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Zhang, Yong-Guo, Zhu, Xiaorong, Lu, Rong, Messer, Jeannette S., Xia, Yinglin, Chang, Eugene B., Sun, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844505/
https://ncbi.nlm.nih.gov/pubmed/30894054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596485
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