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Intestinal epithelial HMGB1 inhibits bacterial infection via STAT3 regulation of autophagy
Extracellular HMGB1 (high mobility group box 1) is considered as a damage-associated molecular pattern protein. However, little is known about its intracellular role. We studied the mechanism whereby intestinal epithelial HMGB1 contributes to host defense, using cell culture, colonoids, conditional...
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| Pubblicato in: | Autophagy |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844505/ https://ncbi.nlm.nih.gov/pubmed/30894054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596485 |
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