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Beneficial effect of STAT3 decoy oligodeoxynucleotide transfection on organ injury and mortality in mice with cecal ligation and puncture-induced sepsis

Sepsis is a major clinical challenge with unacceptably high mortality. The signal transducers and activators of transcription (STAT) family of transcription factors is known to activate critical mediators of cytokine responses, and, among this family, STAT3 is implicated to be a key transcription fa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Imbaby, Samar, Matsuda, Naoyuki, Tomita, Kengo, Hattori, Kohshi, Palikhe, Sailesh, Yokoo, Hiroki, Hattori, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498613/
https://ncbi.nlm.nih.gov/pubmed/32943679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72136-x
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