Neurodegenerative Evidence in Mice Brains with Cecal Ligation and Puncture-Induced Sepsis: Preventive Effect of the Free Radical Scavenger Edaravone

Sepsis is a major clinical challenge and septic encephalopathy is its nasty complication. The pathogenesis and underlying mechanisms of septic encephalopathy are not well understood. This study sought to fully characterize sepsis-associated biochemical and histopathological changes in brains of mice...

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Autors principals: Yokoo, Hiroki, Chiba, Seiichi, Tomita, Kengo, Takashina, Michinori, Sagara, Hiroshi, Yagisita, Saburo, Takano, Yasuo, Hattori, Yuichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517559/
https://ncbi.nlm.nih.gov/pubmed/23236515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051539
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