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Exploring the effect of nsSNPs in human YPEL3 gene in cellular senescence

YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants—V40M, C61Y, G98R, G108S, and A131...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Singh, Abhishek, Thakur, Mukesh, Singh, Sujeet Kumar, Sharma, Lalit Kumar, Chandra, Kailash
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498449/
https://ncbi.nlm.nih.gov/pubmed/32943700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72333-8
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