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Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach

BACKGROUND: Distinguishing the deleterious from the massive number of non-functional nsSNPs that occur within a single genome is a considerable challenge in mutation research. In this approach, we have used the existing in silico methods to explore the mutation-structure-function relationship in the...

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Detalhes bibliográficos
Main Authors: NagaSundaram, N, Priya Doss, C George
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243084/
https://ncbi.nlm.nih.gov/pubmed/22190868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.90441
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