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Exploring the effect of nsSNPs in human YPEL3 gene in cellular senescence

YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants—V40M, C61Y, G98R, G108S, and A131...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Singh, Abhishek, Thakur, Mukesh, Singh, Sujeet Kumar, Sharma, Lalit Kumar, Chandra, Kailash
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498449/
https://ncbi.nlm.nih.gov/pubmed/32943700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72333-8
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