Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes

Mantle cell lymphoma (MCL) is a mature B-cell neoplasm initially driven by CCND1 rearrangement with 2 molecular subtypes, conventional MCL (cMCL) and leukemic non-nodal MCL (nnMCL), that differ in their clinicobiological behavior. To identify the genetic and epigenetic alterations determining this d...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Nadeu, Ferran, Martin-Garcia, David, Clot, Guillem, Díaz-Navarro, Ander, Duran-Ferrer, Martí, Navarro, Alba, Vilarrasa-Blasi, Roser, Kulis, Marta, Royo, Romina, Gutiérrez-Abril, Jesús, Valdés-Mas, Rafael, López, Cristina, Chapaprieta, Vicente, Puiggros, Montserrat, Castellano, Giancarlo, Costa, Dolors, Aymerich, Marta, Jares, Pedro, Espinet, Blanca, Muntañola, Ana, Ribera-Cortada, Inmaculada, Siebert, Reiner, Colomer, Dolors, Torrents, David, Gine, Eva, López-Guillermo, Armando, Küppers, Ralf, Martin-Subero, Jose I., Puente, Xose S., Beà, Sílvia, Campo, Elias
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2020
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498364/
https://ncbi.nlm.nih.gov/pubmed/32584970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005289
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