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Single-molecule fluorescence studies on cotranscriptional G-quadruplex formation coupled with R-loop formation

G-quadruplex (GQ) is formed at various regions of DNA, including telomeres of chromosomes and regulatory regions of oncogenes. Since GQ is important in both gene regulation and genome instability, the biological and medical implications of this abnormal DNA structure have been intensively studied. I...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lim, Gunhyoung, Hohng, Sungchul
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498336/
https://ncbi.nlm.nih.gov/pubmed/32810236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa695
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