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METTL4 catalyzes m(6)Am methylation in U2 snRNA to regulate pre-mRNA splicing

N (6)-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N(6),2′-O-dimethyladenosine (m(6)Am). Identification of the methyltransferase responsible for m(6)Am catalysis has accelerated studies on the function of m(6)Am in RNA processing. While m(6)Am is generally f...

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Foilsithe in:Nucleic Acids Res
Main Authors: Goh, Yeek Teck, Koh, Casslynn W Q, Sim, Donald Yuhui, Roca, Xavier, Goh, W S Sho
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498333/
https://ncbi.nlm.nih.gov/pubmed/32813009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa684
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