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Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination

Schwann cells are the nerve ensheathing cells of the peripheral nervous system. Absence, loss and malfunction of Schwann cells or their myelin sheaths lead to peripheral neuropathies such as Charcot-Marie-Tooth disease in humans. During Schwann cell development and myelination chromatin is dramatica...

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Pubblicato in:Nucleic Acids Res
Autori principali: Wüst, Hannah M, Wegener, Amélie, Fröb, Franziska, Hartwig, Anna C, Wegwitz, Florian, Kari, Vijayalakshmi, Schimmel, Margit, Tamm, Ernst R, Johnsen, Steven A, Wegner, Michael, Sock, Elisabeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498331/
https://ncbi.nlm.nih.gov/pubmed/32672815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa606
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