Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve

Myelin is essential for the rapidity of saltatory nerve conduction, and also provides trophic support for axons to prevent axonal degeneration. Two critical determinants of myelination are SOX10 and EGR2/KROX20. SOX10 is required for specification of Schwann cells from neural crest, and is required...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Srinivasan, Rajini, Sun, Guannan, Keles, Sunduz, Jones, Erin A., Jang, Sung-Wook, Krueger, Courtney, Moran, John J., Svaren, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Gene Regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413122/
https://ncbi.nlm.nih.gov/pubmed/22492709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks313
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