Active Gene Repression by the Egr2·NAB Complex during Peripheral Nerve Myelination

The Egr2/Krox20 transactivator is required for activation of many myelin-associated genes during peripheral nerve myelination by Schwann cells. However, recent work has indicated that Egr2 not only activates genes required for peripheral nerve myelination but may also be involved in gene repression....

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Autors principals: Mager, Gennifer M., Ward, Rebecca M., Srinivasan, Rajini, Jang, Sung-Wook, Wrabetz, Lawrence, Svaren, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440619/
https://ncbi.nlm.nih.gov/pubmed/18456662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803330200
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