Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination

Schwann cells are the nerve ensheathing cells of the peripheral nervous system. Absence, loss and malfunction of Schwann cells or their myelin sheaths lead to peripheral neuropathies such as Charcot-Marie-Tooth disease in humans. During Schwann cell development and myelination chromatin is dramatica...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Wüst, Hannah M, Wegener, Amélie, Fröb, Franziska, Hartwig, Anna C, Wegwitz, Florian, Kari, Vijayalakshmi, Schimmel, Margit, Tamm, Ernst R, Johnsen, Steven A, Wegner, Michael, Sock, Elisabeth
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Gene regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498331/
https://ncbi.nlm.nih.gov/pubmed/32672815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa606
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