Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network

Lineage specification is governed by gene regulatory networks (GRNs) that integrate the activity of signaling effectors and transcription factors (TFs) on enhancers. Sox17 is a key transcriptional regulator of definitive endoderm development, and yet, its genomic targets remain largely uncharacteriz...

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Опубликовано в: :eLife
Главные авторы: Mukherjee, Shreyasi, Chaturvedi, Praneet, Rankin, Scott A, Fish, Margaret B, Wlizla, Marcin, Paraiso, Kitt D, MacDonald, Melissa, Chen, Xiaoting, Weirauch, Matthew T, Blitz, Ira L, Cho, Ken WY, Zorn, Aaron M
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
Предметы:
Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498262/
https://ncbi.nlm.nih.gov/pubmed/32894225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58029
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