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Morpholinos do not elicit an innate immune response during early Xenopus embryogenesis
Gentsch et al. (2018) recently reported that a common side effect of translation-blocking morpholino antisense oligonucleotides is the induction of a set of innate immune response genes in Xenopus embryos, and that splicing-blocking morpholinos lead to unexpected off-target mis-splicing events. Here...
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| Udgivet i: | Dev Cell |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599594/ https://ncbi.nlm.nih.gov/pubmed/31112700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.04.019 |
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