Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals

CONTEXT: Pancreatic steatosis leading to beta-cell failure might be involved in type 2 diabetes (T2D) pathogenesis. OBJECTIVE: We hypothesized that the genetic background modulates the effect of pancreatic fat on beta-cell function and investigated genotype × pancreatic fat interactions on insulin s...

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Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: Wagner, Róbert, Jaghutriz, Benjamin Assad, Gerst, Felicia, Barroso Oquendo, Morgana, Machann, Jürgen, Schick, Fritz, Löffler, Markus W, Nadalin, Silvio, Fend, Falko, Königsrainer, Alfred, Peter, Andreas, Siegel-Axel, Dorothea, Ullrich, Susanne, Häring, Hans-Ulrich, Fritsche, Andreas, Heni, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Clinical Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497818/
https://ncbi.nlm.nih.gov/pubmed/32725157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa435
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